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KMID : 0358419930360030321
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Korean Journal of Obstetrics and Gynecology
1993 Volume.36 No. 3 p.321 ~ p.325
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Rapid Determination of Fetal Y-Chromosome with Polymerase Chain Reaction
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강성호
정규병/한호원/김영철/노성일/오기석/한인권/문인걸
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Abstract
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Prenatal fetal sex determination is very important in the management of X-linked genetic disorders. The Polymerase chain reaction with Y-chromosome specific DNA sequence is available. We have performed 16 fetal sex determination using the
polymerase
chain reaction and karyotyping method with samples of chorionic villi and amnionic fluid.
We have correctly determined fetal sex within 6 hours by the polymerase chain reaction.
Thus the polymerase chain reaction is a reliable method to determine fetal sex rapidly in the X-linked disorders.
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KEYWORD
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